Deeper pigmentation
The biological effect is an increase in skin pigment. The shade and extent of change depend on your starting skin type and response.
MELANOTAN I
Tanning &
Pigmentation.
Melanotan I stimulates melanin production, the pigment that gives skin its color. Explore how pigmentation changes, the proposed eight-week schedule, and twice-weekly maintenance.
Human injection research has documented increased skin pigmentation. The cosmetic schedule below is a separate proposed example and needs clinical review.
01HOW PIGMENTATION CHANGES
Understand the color.
Track the result.
Melanotan I, also called afamelanotide, acts on melanocortin-1 receptors involved in eumelanin production. Increased pigmentation has been measured in human injection research.
Consistent comparison
Take progress photos under matching lighting and camera settings. Check the same areas to separate a color change from exposure or editing.
Skin protection stays essential
A darker appearance does not replace sunscreen, protective clothing, or shade. Avoid tanning beds and intentional burning.
02PROPOSED SCHEDULE · FOR CLINICAL REVIEW
Eight-week course.
Then maintenance.
The supplied example lists daily amounts for weeks 1–8, followed by 1,000 mcg on Monday and Thursday from week 9.
An example to review, not a validated tanning regimen
The escalation and maintenance schedule below has not been established as safe or effective for cosmetic use. Review it with a qualified clinician before use. Dose increases should never be automatic when symptoms occur.
TIMING IN THIS EXAMPLE
Daily during weeks 1–8
The daily phase includes all seven days of the week. From week 9, the example switches to Monday and Thursday only.
250 mcg
Per dayAll seven days500 mcg
Per dayAll seven days750 mcg
Per dayAll seven days1,000 mcg
Per dayAll seven days1,000 mcg = 1 mg.
Week 9 onward · maintenance
1,000 mcg, twice per week
Monday and Thursday only, with 1,000 mcg per scheduled day. All other days are off.
- SundayOffNo dose
- Monday1 mgScheduled day
- TuesdayOffNo dose
- WednesdayOffNo dose
- Thursday1 mgScheduled day
- FridayOffNo dose
- SaturdayOffNo dose
No maintenance end date is specified in this example. Continued use needs clinical review; the calendar is not a recommendation for indefinite treatment.
03TRACK & PROTECT
Compare consistently.
Protect your skin.
Judge progress through your own skin changes while keeping daily sun protection in place.
Keep photos consistent
Compare the same area in the same lighting. Filters, camera exposure, and seasonal changes can alter how color appears.
Watch the full picture
Record dates, pigment changes, symptoms, and sun exposure. Pay attention to freckles and moles as well as the overall shade.
Maintain sun protection
Use broad-spectrum, water-resistant SPF 30+, protective clothing, and shade. Extra pigment is not a replacement for protection.
04PRACTICAL CARE
Watch your skin.
Listen to symptoms.
Flushing, nausea, and darkening freckles can occur. Review symptoms alongside the cosmetic change.
Keep skin checks in the plan
Have new or changing moles, bleeding lesions, or unusual pigment changes assessed by a dermatologist. Discuss melanoma history and atypical moles before considering injectable Melanotan I.
Review before continuing
Persistent or severe symptoms need medical assessment. Avoid experimental cosmetic use during pregnancy or breastfeeding.
Injection-site comfort
How and where to inject: the illustrated subcutaneous guide.
Itching, redness, or mild swelling can occur after injections. A clean, cool compress can help with mild local discomfort. Seek advice if symptoms persist.
Biofreeze Professional spray is for muscle and joint pain. Its label excludes wounded or irritated skin; it is not recommended here for injection-site itching.
Spreading redness, heat, worsening pain, or fever needs prompt assessment. Trouble breathing, facial swelling, or fainting requires emergency care.